White crystalline powder, odorless

Specific rotation:-49.0 ～-55o

Related substance≤2.0%

Loss on drying≤1.0%

Water≤4.0%

Residue on ignition≤0.2%

Residual Solvents

Dichloromethane≤0.06%

Heptane≤0.5%

Ethyl acetate≤0.5%

Acetone≤0.5%

Ether≤0.5%

Heavy metals≤20ppm

Microbial limits＜0.4 USP/mg

Bacterial endotoxins＜100 CFU/g

Assay(HPLC):97.0~102.0%

Paclitaxel is a monomeric diterpene compound extracted from Chinese yew bark and is a complicated secondary metabolite. Stage II-III clinical studies show that paclitaxel is most suitable for ovarian and breast cancer, and has certain efficacy in treating prostate cancer, lung cancer, colorectal cancer, melanoma, head and neck cancer, esophageal cancer, germ cell tumors, endometrial cancer, lymphoma, brain tumors, bladder cancer, upper gastrointestinal cancer, small cell and non-small cell lung cancer.